Research
www.idebenone.org
Weyer
G, Babeji-Dolle RM, Hadler D, Hofmann S, Herrmann WM, "A controlled study
of 2 doses of idebenone in the treatment of Alzheimer's disease." Neuropsychobiology
1997; 36(2):73-82
Ranen
NG and colleagues, "A controlled trial of idebenone in Huntington's
disease" Mov Disord 1996 Sep; 11(5):549-554
Ikejiri
Y, Mori E, Ishii K, Yasuda M, Sasaki M, "Idebenone improves cerebral
mitochondrial oxidative metabolism in a patient with MELAS" Neurology
1996; Aug 47(2); 583-585.
Pisano
P and colleagues, "Plasma concentrations and pharmacokinetics of idebenone
and its metabolites following single and repeated doses in young patients with
mitochondrial encephalomyopathy." Eur J Pharmacol 1996;
51(2):167-169.
Gillis
JC, Benefield P, McTavish D, "Idebenone, a review of its pharmacodynamic
and pharmacokinetic properties, and therapeutic use in age-related cognitive
disorders." Drugs Aging 1994; Aug;5 (2): 133-152.
Bergamasco
B, Scarzella L, "Idebenone, a
new drug in the treatment of cognitive impariment in patients with dementia of
the Alzheimer type." Funct Neurol 1994; May;9(3):161-168.
Nitta
A, Hasegawa T, "Oral
administration of idebenone, a stimulator of NGF synthesis recovers reduced NGF
content in aged rat brain." Neuosci Lett 1993 Dec 12;
163(2):219-222.
Suno
M, Nagaoka A, "Inhibition of brain mitochondrial swelling by
idebenone."
Arch Gerontol Geriatr 1989 May; 8(3):299-305.
Ihara Y, Namba S, Shiraba T, "Mitochondrial
encephalomyopathy (MELAS), pathological study and successful therapy with
coenzyme Q10 and idebenone." J Neurol Sci 1989 May; 90(3):263-271.
Lerman-Sagie T, Rustin P, Lev D, "Dramatic improvement
in mitochondrial cardiomyopathy following treatment with idebenone."
J Inherit Metab Dis 2001 Feb;24(1):28-34.
Gutzmann H, Hadler D., "Sustained efficacy and
safety of idebenone in the treatment of
Alzheimer's disease: update on a 2-year double-blind multicentre study."
J Neural Transm Suppl 1998;54:301-10.
Yamada K, Nitta A, Hasegawa T, "Orally active NGF synthesis stimulators:
potential therapeutic agents in Alzheimer's disease."
Behav Brain Res 1997 Feb;83(1-2):117-22.
Bergamasco B, Scarzella L, "Idebenone, a new drug
in the treatment of cognitive impairment in patients with dementia of the
Alzheimer type."
Funct Neurol 1994
May-Jun;9(3):161-8.